Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial.

ABSTRACT:

Objective

To assess the magnitude and independence of the effects of routine blood pressure lowering and intensive glucose control on clinical outcomes in patients with long-standing type 2 diabetes.

Research design and methods

This was a multicenter, factorial randomized trial of perindopril-indapamide versus placebo (double-blind comparison) and intensive glucose control with a gliclazide MR-based regimen (target A1C

SUBMITTER: Zoungas S 

PROVIDER: S-EPMC2768202 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature