Association of type 1 diabetes with month of birth among U.S. youth: The SEARCH for Diabetes in Youth Study.

ABSTRACT:

Objective

Seasonal environment at birth may influence diabetes incidence in later life. We sought evidence for this effect in a large sample of diabetic youth residing in the U.S.

Research design and methods

We compared the distribution of birth months within the SEARCH for Diabetes in Youth Study (SEARCH study) with the monthly distributions in U.S. births tabulated by race for years 1982-2005. SEARCH study participants (9,737 youth with type 1 diabetes and 1,749 with type 2 diabetes) were identified by six collaborating U.S. centers.

Results

Among type 1 diabetic youth, the percentage of observed to expected births differed across the months (P = 0.0092; decreased in October-February and increased in March-July). Their smoothed birth-month estimates demonstrated a d

SUBMITTER: Kahn HS 

PROVIDER: S-EPMC2768213 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature