TonB-dependent transporters and their occurrence in cyanobacteria.

ABSTRACT:

Background

Different iron transport systems evolved in Gram-negative bacteria during evolution. Most of the transport systems depend on outer membrane localized TonB-dependent transporters (TBDTs), a periplasma-facing TonB protein and a plasma membrane localized machinery (ExbBD). So far, iron chelators (siderophores), oligosaccharides and polypeptides have been identified as substrates of TBDTs. For iron transport, three uptake systems are defined: the lactoferrin/transferrin binding proteins, the porphyrin-dependent transporters and the siderophore-dependent transporters. However, for cyanobacteria almost nothing is known about possible TonB-dependent uptake systems for iron or other substrates.

Results

We have screened all publicly available eubacterial genomes for sequen

SUBMITTER: Mirus O 

PROVIDER: S-EPMC2771747 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature