Culture-independent microbiological analysis of foley urinary catheter biofilms.

ABSTRACT:

Background

Prevention of catheter-associated urinary tract infection (CAUTI), a leading cause of nosocomial disease, is complicated by the propensity of bacteria to form biofilms on indwelling medical devices [1,2,3,4,5].

Methodology/principal findings

To better understand the microbial diversity of these communities, we report the results of a culture-independent bacterial survey of Foley urinary catheters obtained from patients following total prostatectomy. Two patient subsets were analyzed, based on treatment or no treatment with systemic fluoroquinolone antibiotics during convalescence. Results indicate the presence of diverse polymicrobial assemblages that were most commonly observed in patients who did not receive systemic antibiotics. The communities typically contai

SUBMITTER: Frank DN 

PROVIDER: S-EPMC2771765 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature