Human Plasmodium knowlesi infections in young children in central Vietnam.

ABSTRACT:

Background

Considering increasing reports on human infections by Plasmodium knowlesi in Southeast Asian countries, blood samples collected during two large cross-sectional malariometric surveys carried out in a forested area of central Vietnam in 2004 and 2005 were screened for this parasite.

Methods

Blood samples collected at the 2004 survey and positive for Plasmodium malariae were randomly selected for PCR analysis detecting P. knowlesi. Blood samples collected in 2005 from the same individuals were screened again for P. knowlesi. Positive samples were confirmed by sequencing. Family members of positive cases who participated in both surveys were also screened.

Results

Ninety-five samples with P. malariae mono- or mixed infections identified by species-specific PCR

SUBMITTER: Van den Eede P 

PROVIDER: S-EPMC2773789 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature