Appion: an integrated, database-driven pipeline to facilitate EM image processing.

ABSTRACT: The use of cryoEM and three-dimensional image reconstruction is becoming increasingly common. Our vision for this technique is to provide a straightforward manner in which users can proceed from raw data to a reliable 3D reconstruction through a pipeline that both facilitates management of the processing steps and makes the results at each step more transparent. Tightly integrated with a relational SQL database, Appion is a modular and transparent pipeline that extends existing software applications and procedures. The user manages and controls the software modules via web-based forms, and all results are similarly available using web-based viewers directly linked to the underlying database, enabling even naive users to quickly deduce the quality of their results. The Appion API was design

SUBMITTER: Lander GC 

PROVIDER: S-EPMC2775544 | biostudies-literature | 2009 Apr

REPOSITORIES: biostudies-literature