Clinical trial participant characteristics and saliva and DNA metrics.

ABSTRACT:

Background

Clinical trial and epidemiological studies need high quality biospecimens from a representative sample of participants to investigate genetic influences on treatment response and disease. Obtaining blood biospecimens presents logistical and financial challenges. As a result, saliva biospecimen collection is becoming more frequent because of the ease of collection and lower cost. This article describes an assessment of saliva biospecimen samples collected through the mail, trial participant demographic and behavioral characteristics, and their association with saliva and DNA quantity and quality.

Methods

Saliva biospecimens were collected using the Oragene(R) DNA Self-Collection Kits from participants in a National Cancer Institute funded smoking cessation trial. S

SUBMITTER: Nishita DM 

PROVIDER: S-EPMC2776600 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature