Ontology highlight
ABSTRACT:
SUBMITTER: Tenesa A
PROVIDER: S-EPMC2778004 | biostudies-literature | 2008 May
REPOSITORIES: biostudies-literature
Nature genetics 20080330 5
In a genome-wide association study to identify loci associated with colorectal cancer (CRC) risk, we genotyped 555,510 SNPs in 1,012 early-onset Scottish CRC cases and 1,012 controls (phase 1). In phase 2, we genotyped the 15,008 highest-ranked SNPs in 2,057 Scottish cases and 2,111 controls. We then genotyped the five highest-ranked SNPs from the joint phase 1 and 2 analysis in 14,500 cases and 13,294 controls from seven populations, and identified a previously unreported association, rs3802842 ...[more]