The impact of obesity on oxygen desaturation during sleep-disordered breathing.

ABSTRACT:

Rationale

Obesity increases the risk and severity of sleep-disordered breathing. The degree to which excess body weight contributes to blood oxygen desaturation during hypopneic and apneic events has not been comprehensively characterized.

Objectives

To quantify the association between excess body weight and oxygen desaturation during sleep-disordered breathing.

Methods

A total of 750 adult participants in the Wisconsin Sleep Cohort Study were assessed for body mass index (BMI) (kg/m(2)) and sleep-disordered breathing. The amount of Sa(O(2)), duration, and other characteristics of 37,473 observed breathing events were measured during polysomnography studies. A mixed-effects linear regression model estimated the association of blood oxygen desaturation with participant

SUBMITTER: Peppard PE 

PROVIDER: S-EPMC2778152 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature