Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial.

ABSTRACT:

Aims

Assess the efficacy and safety of saxagliptin added to a submaximal sulphonylurea dose vs. uptitration of sulphonylurea monotherapy in patients with type 2 diabetes and inadequate glycaemic control with sulphonylurea monotherapy.

Methods and patients

A total of 768 patients (18-77 years; HbA(1c) screening >or= 7.5 to ResultsAt week 24, 92% of glyburide-only patients were uptitrated to a total glyburide dose of 15 mg/day. Sax

SUBMITTER: Chacra AR 

PROVIDER: S-EPMC2779994 | biostudies-literature | 2009 Sep

REPOSITORIES: biostudies-literature