Maize inbreds exhibit high levels of copy number variation (CNV) and presence/absence variation (PAV) in genome content.

ABSTRACT: Following the domestication of maize over the past approximately 10,000 years, breeders have exploited the extensive genetic diversity of this species to mold its phenotype to meet human needs. The extent of structural variation, including copy number variation (CNV) and presence/absence variation (PAV), which are thought to contribute to the extraordinary phenotypic diversity and plasticity of this important crop, have not been elucidated. Whole-genome, array-based, comparative genomic hybridization (CGH) revealed a level of structural diversity between the inbred lines B73 and Mo17 that is unprecedented among higher eukaryotes. A detailed analysis of altered segments of DNA conservatively estimates that there are several hundred CNV sequences among the two genotypes, as well as several t

SUBMITTER: Springer NM 

PROVIDER: S-EPMC2780416 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature