Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus.

ABSTRACT: The impact of globalization on the emergence and spread of pathogens is an important veterinary and public health issue. Staphylococcus aureus is a notorious human pathogen associated with serious nosocomial and community-acquired infections. In addition, S. aureus is a major cause of animal diseases including skeletal infections of poultry, which are a large economic burden on the global broiler chicken industry. Here, we provide evidence that the majority of S. aureus isolates from broiler chickens are the descendants of a single human-to-poultry host jump that occurred approximately 38 years ago (range, 30 to 63 years ago) by a subtype of the worldwide human ST5 clonal lineage unique to Poland. In contrast to human subtypes of the ST5 radiation, which demonstrate strong geographic clust

SUBMITTER: Lowder BV 

PROVIDER: S-EPMC2780746 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature