Myxococcus xanthus Pph2 is a manganese-dependent protein phosphatase involved in energy metabolism.

ABSTRACT: The multicellular behavior of the myxobacterium Myxococcus xanthus requires the participation of an elevated number of signal-transduction mechanisms to coordinate the cell movements and the sequential changes in gene expression patterns that lead to the morphogenetic and differentiation events. These signal-transduction mechanisms are mainly based on two-component systems and on the reversible phosphorylation of protein targets mediated by eukaryotic-like protein kinases and phosphatases. Among all these factors, protein phosphatases are the elements that remain less characterized. Hence, we have studied in this work the physiological role and biochemical activity of the protein phosphatase of the family PPP (phosphoprotein phosphatases) designated as Pph2, which is forming part of the sa

SUBMITTER: Garcia-Hernandez R 

PROVIDER: S-EPMC2781417 | biostudies-literature | 2009 Oct

REPOSITORIES: biostudies-literature