Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C.

ABSTRACT:

Unlabelled

Higher coffee consumption has been associated inversely with the incidence of chronic liver disease in population studies. We examined the relationship of coffee consumption with liver disease progression in individuals with advanced hepatitis C-related liver disease. Baseline coffee and tea intake were assessed in 766 participants of the Hepatitis C Antiviral Long-Term Treatment against Cirrhosis (HALT-C) trial who had hepatitis C-related bridging fibrosis or cirrhosis on liver biopsy and failed to achieve a sustained virological response to peginterferon plus ribavirin treatment. Participants were followed for 3.8 years for clinical outcomes and, for those without cirrhosis, a 2-point increase in Ishak fibrosis score on protocol biopsies. At baseline, higher coffee con

SUBMITTER: Freedman ND 

PROVIDER: S-EPMC2783828 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature