Ontology highlight
ABSTRACT:
SUBMITTER: Swetloff A
PROVIDER: S-EPMC2785738 | biostudies-literature | 2009 Dec
REPOSITORIES: biostudies-literature
Swetloff Adam A Conne Beatrice B Huarte Joachim J Pitetti Jean-Luc JL Nef Serge S Vassalli Jean-Dominique JD
Molecular biology of the cell 20091007 23
Processing bodies (P-bodies) are cytoplasmic granules involved in the storage and degradation of mRNAs. In somatic cells, their formation involves miRNA-mediated mRNA silencing. Many P-body protein components are also found in germ cell granules, such as in mammalian spermatocytes. In fully grown mammalian oocytes, where changes in gene expression depend entirely on translational control, RNA granules have not as yet been characterized. Here we show the presence of P-body-like foci in mouse oocy ...[more]