Severity of CIND and MCI predict incidence of dementia in an ischemic stroke cohort.

ABSTRACT:

Background

The utility of poststroke cognitive status, namely dementia, cognitive impairment no dementia (CIND), mild cognitive impairment (MCI), and no cognitive impairment (NCI), in predicting dementia has been previously examined. However, no studies to date have compared the ability of subtypes of MCI and CIND to predict dementia in a poststroke population.

Methods

A cohort of ischemic stroke patients underwent neuropsychological assessment annually for up to 5 years. Dementia was defined using the DSM-IV criteria. Univariate and multivariable Cox proportional regression was performed to determine the ability of MCI subtypes, CIND severity, and individual domains of impairment to predict dementia.

Results

A total of 362 patients without dementia were followed up f

SUBMITTER: Narasimhalu K 

PROVIDER: S-EPMC2788800 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature