MicroScope: a platform for microbial genome annotation and comparative genomics.

ABSTRACT: The initial outcome of genome sequencing is the creation of long text strings written in a four letter alphabet. The role of in silico sequence analysis is to assist biologists in the act of associating biological knowledge with these sequences, allowing investigators to make inferences and predictions that can be tested experimentally. A wide variety of software is available to the scientific community, and can be used to identify genomic objects, before predicting their biological functions. However, only a limited number of biologically interesting features can be revealed from an isolated sequence. Comparative genomics tools, on the other hand, by bringing together the information contained in numerous genomes simultaneously, allow annotators to make inferences based on the idea that e

SUBMITTER: Vallenet D 

PROVIDER: S-EPMC2790312 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature