Synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid and structure of its metal-bridging complex with human arginase I.

ABSTRACT: The synthesis of (2S)-2-amino-7,8-epoxyoctanoic acid is reported along with the X-ray crystal structure of its complex with human arginase I, revealing unique coordination interactions with two manganese ions in the enzyme active site.

SUBMITTER: Zakharian TY 

PROVIDER: S-EPMC2790808 | biostudies-literature | 2008 Sep

REPOSITORIES: biostudies-literature