Synthesis of (-)-berkelic acid.

ABSTRACT: An extremophilic challenge: Stereospecific condensation of a fully functionalized ketal aldehyde and a 2,6-dihydroxybenzoic acid is the key step in the synthesis of (-)-berkelic acid confirming Fürstner's reassignment of the stereochemistry at C18 and C19, establishing the absolute stereochemistry, and tentatively assigning the stereochemistry at C22.

SUBMITTER: Wu X 

PROVIDER: S-EPMC2790819 | biostudies-literature | 2009

REPOSITORIES: biostudies-literature