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An aromatic Glaser-Hay reaction.

ABSTRACT: A general method for copper-catalyzed deprotonative dimerization of arenes by employing oxygen as the terminal oxidant has been developed. Electron-rich and electron-poor heterocycles as well as electron-poor arenes are reactive. The method is tolerant to functionalities such as nitro, cyano, dialkylamino, and ester groups.

SUBMITTER: Do HQ

PROVIDER: S-EPMC2791693 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature

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An aromatic Glaser-Hay reaction.

Do Hien-Quang HQ Daugulis Olafs O

Journal of the American Chemical Society 20091201 47

A general method for copper-catalyzed deprotonative dimerization of arenes by employing oxygen as the terminal oxidant has been developed. Electron-rich and electron-poor heterocycles as well as electron-poor arenes are reactive. The method is tolerant to functionalities such as nitro, cyano, dialkylamino, and ester groups. ...[more]

PMID: 19899771

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