A comparison of fMRI adaptation and multivariate pattern classification analysis in visual cortex.

ABSTRACT: Functional magnetic resonance imaging (fMRI) has become a ubiquitous tool in cognitive neuroscience. The technique allows noninvasive measurements of cortical responses in the human brain, but only on the millimeter scale. Because a typical voxel contains many thousands of neurons with varied properties, establishing the selectivity of their responses directly is impossible. In recent years, two methods using fMRI aimed at studying the selectivity of neuronal populations on a 'subvoxel' scale have been heavily used. The first technique, fMRI adaptation, relies on the observation that the blood oxygen level-dependent (BOLD) response in a given voxel is reduced after prolonged presentation of a stimulus, and that this reduction is selective to the characteristics of the repeated stimuli (ada

SUBMITTER: Sapountzis P 

PROVIDER: S-EPMC2793370 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature