Systems analysis of plant cell wall degradation by the model filamentous fungus Neurospora crassa.

ABSTRACT: The filamentous fungus Neurospora crassa is a model laboratory organism, but in nature is commonly found growing on dead plant material, particularly grasses. Using functional genomics resources available for N. crassa, which include a near-full genome deletion strain set and whole genome microarrays, we undertook a system-wide analysis of plant cell wall and cellulose degradation. We identified approximately 770 genes that showed expression differences when N. crassa was cultured on ground Miscanthus stems as a sole carbon source. An overlap set of 114 genes was identified from expression analysis of N. crassa grown on pure cellulose. Functional annotation of up-regulated genes showed enrichment for proteins predicted to be involved in plant cell wall degradation, but also many genes enco

SUBMITTER: Tian C 

PROVIDER: S-EPMC2794032 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature