The association between alcohol use, alcohol use disorders and tuberculosis (TB). A systematic review.

ABSTRACT:

Background

In 2004, tuberculosis (TB) was responsible for 2.5% of global mortality (among men 3.1%; among women 1.8%) and 2.2% of global burden of disease (men 2.7%; women 1.7%). The present work portrays accumulated evidence on the association between alcohol consumption and TB with the aim to clarify the nature of the relationship.

Methods

A systematic review of existing scientific data on the association between alcohol consumption and TB, and on studies relevant for clarification of causality was undertaken.

Results

There is a strong association between heavy alcohol use/alcohol use disorders (AUD) and TB. A meta-analysis on the risk of TB for these factors yielded a pooled relative risk of 2.94 (95% CI: 1.89-4.59). Numerous studies show pathogenic impact of alcoh

SUBMITTER: Rehm J 

PROVIDER: S-EPMC2796667 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature