Comparative analysis of catfish BAC end sequences with the zebrafish genome.

ABSTRACT:

Background

Comparative mapping is a powerful tool to transfer genomic information from sequenced genomes to closely related species for which whole genome sequence data are not yet available. However, such an approach is still very limited in catfish, the most important aquaculture species in the United States. This project was initiated to generate additional BAC end sequences and demonstrate their applications in comparative mapping in catfish.

Results

We reported the generation of 43,000 BAC end sequences and their applications for comparative genome analysis in catfish. Using these and the additional 20,000 existing BAC end sequences as a resource along with linkage mapping and existing physical map, conserved syntenic regions were identified between the catfish and zebr

SUBMITTER: Liu H 

PROVIDER: S-EPMC2796685 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature