"Hot standards" for the thermoacidophilic archaeon Sulfolobus solfataricus.

ABSTRACT: Within the archaea, the thermoacidophilic crenarchaeote Sulfolobus solfataricus has become an important model organism for physiology and biochemistry, comparative and functional genomics, as well as, more recently also for systems biology approaches. Within the Sulfolobus Systems Biology ("SulfoSYS")-project the effect of changing growth temperatures on a metabolic network is investigated at the systems level by integrating genomic, transcriptomic, proteomic, metabolomic and enzymatic information for production of a silicon cell-model. The network under investigation is the central carbohydrate metabolism. The generation of high-quality quantitative data, which is critical for the investigation of biological systems and the successful integration of the different datasets, derived for exa

SUBMITTER: Zaparty M 

PROVIDER: S-EPMC2797409 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature