Ethnic differences in the relationship between albuminuria and calcified atherosclerotic plaque: the African American-diabetes heart study.

ABSTRACT:

Objective

Despite higher rates of nephropathy, calcified atherosclerotic plaque is less prevalent in African Americans with diabetes relative to European Americans. We explored ethnicity-specific relationships between albuminuria and calcified plaque involving the infrarenal aorta, coronary artery, and carotid artery in 835 European American and 393 African American subjects with type 2 diabetes.

Research design and methods

Generalized estimating equations with exchangeable correlation and the sandwich estimator of the variance were used to test for association between the principal component of calcified plaque in the three vascular beds and urine albumin-to-creatinine ratio (ACR).

Results

Mean +/- SD ages of African American and European American participants were 5

SUBMITTER: Divers J 

PROVIDER: S-EPMC2797958 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature