Comparison of A1C and fasting glucose criteria to diagnose diabetes among U.S. adults.

ABSTRACT:

Objective

To compare A1C and fasting glucose for the diagnosis of diabetes among U.S. adults.

Research design and methods

This study included 6,890 adults (> or =20 years of age) from the 1999-2006 National Health and Nutrition Examination Survey without a self-reported history of diabetes who had fasted > or =9 h. A1C > or =6.5% and fasting glucose > or =126 mg/dl were used, separately, to define diabetes.

Results

Overall, 1.8% of U.S. adults had A1C > or =6.5% and fasting glucose > or =126 mg/dl, 0.5% had A1C > or =6.5% and fasting glucose <126 mg/dl, and 1.8% had A1C <6.5% and fasting glucose > or =126 mg/dl. Compared with individuals with A1C <6.5% and fasting glucose > or =126 mg/dl, individuals with A1C > or =6.5% and fasting glucose <126 mg/dl were younger, more likely to be non-Hispanic black, had lower Hb levels, and had higher C-reactive protein.

Conclusions

A1C > or =6.5% demonstrates reasonable agreement with fasting glucose for diagnosing diabetes among U.S. adults.

SUBMITTER: Carson AP 

PROVIDER: S-EPMC2797994 | biostudies-literature |

REPOSITORIES: biostudies-literature