Longitudinal relationships among coronary artery calcification, serum phosphorus, and kidney function.

ABSTRACT:

Background and objectives

Coronary artery calcification (CAC) is common in advanced chronic kidney disease (CKD), yet its onset and time course are uncertain. The study objective was to assess longitudinal relationships among CAC, kidney function, and traditional and putative cardiovascular disease (CVD) risk factors.

Design, setting, participants, & measurements

This is a prospective cohort analysis from the Spokane Heart Study, a long-term observational study of community-dwelling adults who were assessed every 2 yr for CAC (electron-beam computed tomography), CVD risk factors, and laboratory testing. Estimated GFR (eGFR) was determined by the reexpressed Modification of Diet in Renal Disease equation.

Results

CAC was present in 28% (245 of 883) at baseline. After 6

SUBMITTER: Tuttle KR 

PROVIDER: S-EPMC2798869 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature