Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair.

ABSTRACT:

Objective

To determine whether limiting intraoperative sedation depth during spinal anesthesia for hip fracture repair in elderly patients can decrease the prevalence of postoperative delirium.

Patients and methods

We performed a double-blind, randomized controlled trial at an academic medical center of elderly patients (>or=65 years) without preoperative delirium or severe dementia who underwent hip fracture repair under spinal anesthesia with propofol sedation. Sedation depth was titrated using processed electroencephalography with the bispectral index (BIS), and patients were randomized to receive either deep (BIS, approximately 50) or light (BIS, >or=80) sedation. Postoperative delirium was assessed as defined by Diagnostic and Statistical Manual of Mental Disorders (Thi

SUBMITTER: Sieber FE 

PROVIDER: S-EPMC2800291 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature