Suzuki-Miyaura coupling of aryl carbamates, carbonates, and sulfamates.

ABSTRACT: The first Suzuki-Miyaura cross-couplings of carbamates, carbonates, and sulfamates is described. The method provides a powerful means of using simple derivatives of phenol as precursors to polysubstituted aromatic compounds, as exemplified by a concise synthesis of the anti-inflammatory drug flurbiprofen.

SUBMITTER: Quasdorf KW 

PROVIDER: S-EPMC2801021 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature