Hepatitis G virus infection in Egyptian children with chronic renal failure (single centre study).

ABSTRACT:

Background

Hepatitis G virus (HGV) is an RNA virus. It is mainly transmitted through exposure to contaminated blood although other routes may also exist. Patients with chronic renal failure (CRF) are at high risk of acquiring HGV because they require frequent blood transfusions. Ongoing HGV infection can be only diagnosed by demonstrating viremia in patient sample by reverse transcriptase (RT) PCR. Antibodies to the envelop protein E2 (anti E2) of HGV is an indicator of virus clearance and testify past HGV contact. This cross sectional study was done to assess the frequency of HGV exposure (ongoing and past infection) in Egyptian children with CRF and to study the possible risk factors of infection.

Methods

This study included 100 children with CRF [34 on regular haemodialys

SUBMITTER: Hammad AM 

PROVIDER: S-EPMC2804678 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature