Ranges of control in the transcriptional regulation of Escherichia coli.

ABSTRACT:

Background

The positioning of genes in the genome is an important evolutionary degree of freedom for organizing gene regulation. Statistical properties of these distributions have been studied particularly in relation to the transcriptional regulatory network. The systematics of gene-gene distances then become important sources of information on the control, which different biological mechanisms exert on gene expression.

Results

Here we study a set of categories, which has to our knowledge not been analyzed before. We distinguish between genes that do not participate in the transcriptional regulatory network (i.e. that are according to current knowledge not producing transcription factors and do not possess binding sites for transcription factors in their regulatory region),

SUBMITTER: Sonnenschein N 

PROVIDER: S-EPMC2804738 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature