Homocysteine levels in chronic gastritis and other conditions: relations to incident cardiovascular disease and dementia.

ABSTRACT:

Background

Homocysteine levels in circulation are determined by several factors and hyperhomocysteinemia is reportedly associated with cardiovascular diseases and dementia. The aim of this study is to determine the relation of chronic gastritis and other conditions to homocysteine levels and their relation to incident cardiovascular diseases and dementia.

Methods

An adult population-based cohort (N = 488) was screened for H. pylori infection, gastro-duodenitis (endoscopic biopsies), disease history, and lifestyle factors. Blood samples were analyzed for pepsinogen I and II (gastric function), vitamin B12, folate, homocysteine, and cystatin C (renal function). The methylenetetrahydrofolate reductase C677T polymorphism reportedly associated with hyperhomocysteinemia was analyz

SUBMITTER: Redeen S 

PROVIDER: S-EPMC2804795 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature