Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
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ABSTRACT:
SUBMITTER: Tobias JS
PROVIDER: S-EPMC2806549 | biostudies-literature | 2010 Jan
REPOSITORIES: biostudies-literature
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Chemoradiotherapy for locally advanced head and neck cancer: 10-year follow-up of the UK Head and Neck (UKHAN1) trial.
Tobias Jeffrey S JS Monson Kathryn K Gupta Nirmal N Macdougall Hugh H Glaholm John J Hutchison Iain I Kadalayil Latha L Hackshaw Allan A
The Lancet. Oncology 20091029 1
<h4>Background</h4>Between 1990 and 2000, we examined the effect of timing of non-platinum chemotherapy when combined with radiotherapy. We aimed to determine whether giving chemotherapy concurrently with radiotherapy or as maintenance therapy, or both, affected clinical outcome. Here we report survival and recurrence after 10 years of follow-up.<h4>Methods</h4>Between Jan 15, 1990, and June 20, 2000, 966 patients were recruited from 34 centres in the UK and two centres from Malta and Turkey. Pa ...[more]
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