Radiation exposure and circulatory disease risk: Hiroshima and Nagasaki atomic bomb survivor data, 1950-2003.

ABSTRACT:

Objective

To investigate the degree to which ionising radiation confers risk of mortality from heart disease and stroke.

Design

Prospective cohort study with more than 50 years of follow-up.

Setting

Atomic bomb survivors in Hiroshima and Nagasaki, Japan.

Participants

86 611 Life Span Study cohort members with individually estimated radiation doses from 0 to >3 Gy (86% received <0.2 Gy).

Main outcome measures

Mortality from stroke or heart disease as the underlying cause of death and dose-response relations with atomic bomb radiation.

Results

About 9600 participants died of stroke and 8400 died of heart disease between 1950 and 2003. For stroke, the estimated excess relative risk per gray was 9% (95% confidence interval 1% to 17%, P=0.02) on the ba

SUBMITTER: Shimizu Y 

PROVIDER: S-EPMC2806940 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature