A rho scaffold integrates the secretory system with feedback mechanisms in regulation of auxin distribution.

ABSTRACT: Development in multicellular organisms depends on the ability of individual cells to coordinate their behavior by means of small signaling molecules to form correctly patterned tissues. In plants, a unique mechanism of directional transport of the signaling molecule auxin between cells connects cell polarity and tissue patterning and thus is required for many aspects of plant development. Direction of auxin flow is determined by polar subcellular localization of PIN auxin efflux transporters. Dynamic PIN polar localization results from the constitutive endocytic cycling to and from the plasma membrane, but it is not well understood how this mechanism connects to regulators of cell polarity. The Rho family small GTPases ROPs/RACs are master regulators of cell polarity, however their role in

SUBMITTER: Hazak O 

PROVIDER: S-EPMC2808208 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature