The MiST2 database: a comprehensive genomics resource on microbial signal transduction.

ABSTRACT: The MiST2 database (http://mistdb.com) identifies and catalogs the repertoire of signal transduction proteins in microbial genomes. Signal transduction systems regulate the majority of cellular activities including the metabolism, development, host-recognition, biofilm production, virulence, and antibiotic resistance of human pathogens. Thus, knowledge of the proteins and interactions that comprise these communication networks is an essential component to furthering biomedical discovery. These are identified by searching protein sequences for specific domain profiles that implicate a protein in signal transduction. Compared to the previous version of the database, MiST2 contains a host of new features and improvements including the following: draft genomes; extracytoplasmic function (ECF)

SUBMITTER: Ulrich LE 

PROVIDER: S-EPMC2808908 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature