Cancer linked to Alzheimer disease but not vascular dementia.

ABSTRACT:

Objective

To investigate whether cancer is associated with Alzheimer disease (AD) and vascular dementia (VaD).

Methods

Cox proportional hazards models were used to test associations between prevalent dementia and risk of future cancer hospitalization, and associations between prevalent cancer and risk of subsequent dementia. Participants in the Cardiovascular Health Study-Cognition Substudy, a prospective cohort study, aged 65 years or older (n = 3,020) were followed a mean of 5.4 years for dementia and 8.3 years for cancer.

Results

The presence of any AD (pure AD + mixed AD/VaD; hazard ratio [HR] = 0.41, 95% confidence interval [CI] = 0.20-0.84) and pure AD (HR = 0.31, 95% CI = 0.12-0.86) was associated with a reduced risk of future cancer hospitalization, adjusted f

SUBMITTER: Roe CM 

PROVIDER: S-EPMC2809029 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature