Performance characteristics of the new definition of diabetes: the insulin resistance atherosclerosis study.

ABSTRACT:

Objective

A1C > or =6.5% has been recently proposed as the defining criterion for diabetes. However, performance characteristics of this definition have not been described.

Research design and methods

In the Insulin Resistance Atherosclerosis Study, we compared new to previous definitions of diabetes: 1999 World Health Organization (DM(1999WHO)) and 2003 American Diabetes Association based on fasting glucose alone (DM(FPG126)).

Results

Participants with A1C > or =6.5%, DM(1999WHO), and DM(FPG126) were 44 (5.2%), 132 (15.4%), and 61 (7.1%), respectively. In individuals with DM(1999WHO), mean, median, and interquartile range of A1C were 6.3, 5.9, and 5.5-6.6%, respectively; in individuals with DM(FPG126), mean, median, and interquartile range of A1C were 7.0, 6.6, and 6

SUBMITTER: Lorenzo C 

PROVIDER: S-EPMC2809276 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature