Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology.

ABSTRACT: Pathway Tools is a production-quality software environment for creating a type of model-organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc integrates the evolving understanding of the genes, proteins, metabolic network and regulatory network of an organism. This article provides an overview of Pathway Tools capabilities. The software performs multiple computational inferences including prediction of metabolic pathways, prediction of metabolic pathway hole fillers and prediction of operons. It enables interactive editing of PGDBs by DB curators. It supports web publishing of PGDBs, and provides a large number of query and visualization tools. The software also supports comparative analyses of PGDBs, and provides several systems biology analyses of PGDBs includi

SUBMITTER: Karp PD 

PROVIDER: S-EPMC2810111 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature