Efficient synthesis of B-alkylated oxazaborolidines derived from ephedrine and norephedrine.

ABSTRACT: [reaction: see text] Representative B-butyl- and B-methyl-1,3,2-oxazaborolidines derived from ephedrine and norephedrine were prepared in good yield and excellent purity by one-pot treatment of B-H oxazaborolidines with the corresponding organolithium reagent and subsequent hydrolysis of the cyclic borohydride intermediate with anhydrous ammonium chloride.

SUBMITTER: Ortiz-Marciales M 

PROVIDER: S-EPMC2811074 | biostudies-literature | 2003 Sep

REPOSITORIES: biostudies-literature