Impact of mucosal eosinophilia and nasal polyposis on quality-of-life outcomes after sinus surgery.

ABSTRACT:

Objective

Assess whether the presence of mucosal eosinophilia correlates with surgical outcomes in patients with chronic rhinosinusitis.

Study design

Prospective cohort.

Setting

Tertiary medical center.

Subjects and methods

Adult patients with chronic rhinosinusitis were prospectively enrolled, and demographic data and medical comorbidities were recorded. Preoperative quality of life (QOL) was measured by the Chronic Sinusitis Survey (CSS), Rhinosinusitis Disability Index (RSDI), and Short Form-36 General Health Survey (SF-36). Sinus mucosal specimens were collected at the time of surgery and the degree of eosinophilia quantified. Postoperative QOL was measured, and differences in QOL improvement were compared between those with and without eosinophilia.

Res

SUBMITTER: Soler ZM 

PROVIDER: S-EPMC2811855 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature