Long-term observation of subunit vaccine F1-rV270 against Yersinia pestis in mice.

ABSTRACT: Long-term protection and antibody response for the subunit vaccine F1-rV270 were determined by using the mouse model. Antibodies to F1 and rV270 were still detectable over a period of 518 days. The complete protection against lethal challenge of Yersinia pestis could be achieved up to day 518 after primary immunization.

SUBMITTER: Wang Z 

PROVIDER: S-EPMC2812077 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature