Catalytic enantioselective formation of chiral-bridged dienes which are themselves ligands for enantioselective catalysis.

ABSTRACT: This paper reports a method for highly enantioselective Diels-Alder reaction with an acetylene equivalent to produce chiral-bridged dienes. These dienes, by coordination to Rh(I), can serve as catalysts for the enantioselective addition of vinyl or aryl groups to alpha,beta-unsaturated ketones.

SUBMITTER: Brown MK 

PROVIDER: S-EPMC2814301 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature