Adolescent type 1 Diabetes Cardio-renal Intervention Trial (AdDIT).

ABSTRACT:

Background

The prognosis for young people diagnosed with diabetes during childhood remains poor and this is mainly related to the long-term risk of developing vascular complications.Microalbuminuria identifies subjects at risk for diabetic nephropathy (DN) and cardiovascular disease (CVD). It is often detected in adolescence but is rarely treated before the age of 18 years, as at the end of puberty albumin excretion may decline and in some subjects will return into the normal range. However, evidence indicates that subjects with both transient and persistent microalbuminuria have experienced renal damage during puberty and thus reno-protection to prevent long-term complications is warranted. In adults with diabetes and microalbuminuria, the use of angiotensin converting enzyme inhi

SUBMITTER: Adolescent type 1 Diabetes cardio-renal Intervention Trial Research Group 

PROVIDER: S-EPMC2814806 | biostudies-literature | 2009 Dec

REPOSITORIES: biostudies-literature