In vivo evaluation of the presence of bone marrow in cortical porosity in postmenopausal osteopenic women.

ABSTRACT: This is the first observational study examining cortical porosity in vivo in postmenopausal osteopenic women and to incorporate data from two different imaging modalities to further examine the nature of cortical porosity. The goal of this study was to combine high-resolution peripheral computed tomography (HR-pQCT) images, which contain high spatial resolution information of the cortical structure, and magnetic resonance (MR) images, which allow the visualization of soft tissues such as bone marrow, to observe the amount of cortical porosity that contains bone marrow in postmenopausal osteopenic women. The radius of 49 and the tibia of 51 postmenopausal osteopenic women (age 56 +/- 3.7) were scanned using both HR-pQCT and MR imaging. A normalized mutual information registration algorithm

SUBMITTER: Goldenstein J 

PROVIDER: S-EPMC2815796 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature