Sleep deprivation impairs object-selective attention: a view from the ventral visual cortex.

ABSTRACT:

Background

Most prior studies on selective attention in the setting of total sleep deprivation (SD) have focused on behavior or activation within fronto-parietal cognitive control areas. Here, we evaluated the effects of SD on the top-down biasing of activation of ventral visual cortex and on functional connectivity between cognitive control and other brain regions.

Methodology/principal findings

Twenty-three healthy young adult volunteers underwent fMRI after a normal night of sleep (RW) and after sleep deprivation in a counterbalanced manner while performing a selective attention task. During this task, pictures of houses or faces were randomly interleaved among scrambled images. Across different blocks, volunteers responded to house but not face pictures, face but not hou

SUBMITTER: Lim J 

PROVIDER: S-EPMC2816724 | biostudies-literature | 2010 Feb

REPOSITORIES: biostudies-literature