Knowledge creation: synthesis, tools and products.
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ABSTRACT:
SUBMITTER: Brouwers M
PROVIDER: S-EPMC2817339 | biostudies-literature | 2010 Feb
REPOSITORIES: biostudies-literature
Publications
Knowledge creation: synthesis, tools and products.
Brouwers Melissa M Stacey Dawn D O'Connor Annette A
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20091102 2
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Project description:BackgroundPositive impacts of quality improvement initiatives on health care and services have not been substantial. Knowledge translation (KT) strategies (tools, products and interventions) strive to facilitate the uptake of knowledge thereby the potential to improve care, but there is little guidance on how to develop them. Existing KT guidance or planning tools fall short in operationalizing all aspects of KT practice activities conducted by knowledge users (researchers, clinicians, patients, decision-makers), and most do not consider their variable needs or to deliver recommendations that are most relevant and useful for them.MethodsWe conducted a 3-phase study. In phase 1, we used several sources to develop a conceptual framework for creating optimized Knowledge-activated Tools (KaT) (consultation with our integrated KT team, the use of existing KT models and frameworks, findings of a systematic review of multimorbidity interventions and a literature review and document analysis on existing KT guidance tools). In phase 2, we invited KT experts to participate in a Delphi study to refine and evaluate the conceptual KaT framework. In phase 3, we administered an online survey to knowledge users (researchers, clinicians, decision-makers, trainees) to evaluate the potential usefulness of an online mock-up version of the KaT framework.ResultsWe developed the conceptual KaT framework, and iteratively refined it with 35 KT experts in a 3-round Delphi study. The final framework represents the blueprint for what is needed to create KT strategies. Feedback from 201 researcher, clinician, decision-maker and trainee knowledge users on the potential need and usefulness of an online, interactive version of KaT indicated that they liked the idea of it (mean score 4.36 on a 5-point Likert scale) and its proposed features (mean score range 4.30-4.79).ConclusionsOur findings suggest that mostly Canadian KT experts and knowledge users perceived the KaT framework and the future development of an online, interactive version to be important and needed. We anticipate that the KaT framework will provide clarity for knowledge users about how to identify their KT needs and what activities can address these needs, and to help streamline the process of these activities to facilitate efficient uptake of knowledge.
| S-EPMC7427906 | biostudies-literature
Project description:BackgroundDespite far reaching support for integrated care, conceptualizing and measuring integrated care remains challenging. This knowledge synthesis aimed to identify indicator domains and tools to measure progress towards integrated care.MethodsWe used an established framework and a Delphi survey with integration experts to identify relevant measurement domains. For each domain, we searched and reviewed the literature for relevant tools.FindingsFrom 7,133 abstracts, we retrieved 114 unique tools. We found many quality tools to measure care coordination, patient engagement and team effectiveness/performance. In contrast, there were few tools in the domains of performance measurement and information systems, alignment of organizational goals and resource allocation. The search yielded 12 tools that measure overall integration or three or more indicator domains.DiscussionOur findings highlight a continued gap in tools to measure foundational components that support integrated care. In the absence of such targeted tools, "overall integration" tools may be useful for a broad assessment of the overall state of a system.ConclusionsContinued progress towards integrated care depends on our ability to evaluate the success of strategies across different levels and context. This study has identified 114 tools that measure integrated care across 16 domains, supporting efforts towards a unified measurement framework.
| S-EPMC5854167 | biostudies-literature
Project description:Under the theoretical approaches of the resource-based view of the firm, the dynamic capabilities and the knowledge-based view of the firm, the purpose of this paper is to analyze the influence that the knowledge management infrastructure has on knowledge creation processes in primary sector companies, specifically, the aquaculture sector. For the empirical analysis, the SEM-PLS approach was used on a sample of 186 shrimp farms in Ecuador. Results confirm that the environment and organizational structure, and culture influence knowledge creation, while technological resources are not significant. This can be explained by the characteristics of the central activities of the shrimp companies and the assignment of functions. From a theoretical point of view, this paper links the knowledge-based view of the firm with the activities of the primary sector. Specifically, a theoretical model is developed in which the variables that can influence the knowledge creation processes of shrimp farms are studied. Existing works in the scientific literature that analyze both perspectives are practically nil. From a managerial perspective, given the importance of the creation and renewal of knowledge to develop organizational capabilities in the face of the dynamism of the market, the findings of this study can guide managers to understand how the combination of resources can help increase stocks of knowledge useful to business objectives.
| S-EPMC10558717 | biostudies-literature
Project description:Regenerative medicine is currently the focus of global attention. Countries all around the world are actively working to create new regenerative treatment modalities through pioneering research and novel technologies. This is wonderful news for patients who could not be treated with existing medical options. New venture businesses and companies are being established in regenerative medicine and their rapid industrialization is anticipated. However, to ensure high-quality products, human resources qualified in research and development and the manufacturing of these products are essential. The Forum for Innovative Regenerative Medicine (FIRM) conducted a questionnaire of its industry members to examine the training and hiring of people in research and development, product creation, manufacturing, and more. Regenerative medicine is a brand new field; thus, many different businesses will need to cooperate together. People with a broad range of technical skills, abilities, and knowledge will be in demand, with various levels of expertise, from basic to advanced.
| S-EPMC6134916 | biostudies-literature
Project description:IntroductionEnhanced Recovery After Surgery (ERAS) guidelines integrate evidence-based practices into multimodal care pathways designed to optimise patient recovery following surgery. The objective of this project is to create an ERAS protocol for neonatal abdominal surgery. The protocol will identify and attempt to bridge the gaps between current practices and best evidence. Our study is the first paediatric ERAS protocol endorsed by the International ERAS Society.MethodsA research team consisting of international clinical and family stakeholders as well as methodological experts have iteratively defined the scope of the protocol in addition to individual topic areas. A modified Delphi method was used to reach consensus. The second phase will include a series of knowledge syntheses involving a rapid review coupled with expert opinion. Potential protocol elements supported by synthesised evidence will be identified. The Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) system will be used to determine strength of recommendations and the quality of evidence. The third phase will involve creation of the protocol using a modified RAND/UCLA Appropriateness Method. Group consensus will be used to rate each element in relation to the quality of evidence supporting the recommendation and the appropriateness for guideline inclusion. This protocol will form the basis of a future implementation study.Ethics and disseminationThis study has been registered with the ERAS Society. Human ethics approval (REB 18-0579) is in place to engage patient families within protocol development. This research is to be published in peer-reviewed journals and will form the care standard for neonatal intestinal surgery.
| S-EPMC6303622 | biostudies-literature
Project description:Using best practices to produce creative, relatable, contextualized health messaging contributes to effective risk communication. During emergency disasters, the landscape of mis- and dis-information demands strategic, collaborative approaches across all stakeholders particularly government and the media to ensure effective public messaging. However, tools for new RCCE practitioners and media agencies such as television producers and advertising firms to rapidly create effective RCCE products are currently not readily available. In response to concerns that vaccine hesitancy may become more evident once a significant proportion of the population had been reached, the Ministry of Communications and Information (MCI) in Singapore launched a public health music video on 2 May 2021, making headlines globally and garnering more than 5 million views worldwide. The video aimed to dispel myths and concerns about vaccinations and encouraged citizens to get their vaccination quickly rather than wait. We aimed to evaluate this video as a case study and articulate why it is an example of good practice in risk communications. Working inductively to identify emergent principles of product creation in this case study and analyzing them against existing RCCE frameworks and recommendations helped develop a practical tool to guide the rapid creation of RCCE products by those who may be unfamiliar to RCCE principles. This tool can help new RCCE practitioners and media agencies to produce effective products in times of crisis. The easy-to-use tool provides a brief checklist that guides rapid creation of RCCE products, including criteria for understanding the target audience, message comprehension, development, reach and impact measurement. Given its derivation from existing RCCE frameworks and health literacy concepts, these can potentially be applied across different modalities and diverse cultures. Future work would include validation of these criteria and evaluation of its utility to strengthen RCCE as core in an emergency response.
| S-EPMC9197119 | biostudies-literature
Project description:Although evolutionary studies of gene function often rely on RNA interference, the ideal approach would use reverse genetics to create null mutations for cross-species comparisons and forward genetics to identify novel genes in each species. We have used transcription activator-like effector nucleases (TALENs) to facilitate both approaches in Caenorhabditis nematodes. First, by combining golden gate cloning and TALEN technology, we can induce frameshifting mutations in any gene. Second, by combining this approach with bioinformatics we can predict and create the resources needed for forward genetic analysis in species like Caenorhabditis briggsae. Although developing genetic model organisms used to require years to isolate marker mutations, balancers, and tools, with TALENs, these reagents can now be produced in months. Furthermore, the analysis of nonsense mutants in related model organisms allows a directed approach for making these markers and tools. When used together, these methods could simplify the adaptation of other organisms for forward and reverse genetics.
| S-EPMC3907053 | biostudies-literature
Project description:PurposeThis study aimed to identify knowledge measurement tools for kidney transplantation (KT) and confirm their assessment methods, domains, and validity to provide useful information.DesignAn integrative review based on Whittemore and Knafl's (2005) framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) 2020 guidelines.MethodsAn integrative search was conducted using four English databases (PubMed, Embase, CINAHL, and the Cochrane Library) and the top three Korean databases (RISS, DBpia, and KISS). Search terms and strategies included ("kidney transplant*" OR "renal transplant*" OR "kidney replace*" OR "renal replace*" OR "kidney graft" OR "renal graft") & (knowledge OR awareness) & (scale OR tool OR instrument OR questionnaire OR inventory). The time limit was set to February 2022. The extracted data included the content of the tools, participants, and psychometrics. Quality of life was assessed using a psychometric grading framework.ResultsA total of 15 studies and 13 tools were reviewed. Of these, seven studies (46.7%) targeted KT patients, five (33.3%) targeted KT candidates, and three (20.0%) included both groups. The number of items in the tools ranged from five to 33 items. Furthermore, seven tools comprised true-false questions and eight multiple-choice questions. The domains of the KT knowledge measurement tool used in each study differed across study participants. Both reliability and validity were confirmed in six tools, and only two showed a grade of "adequate" or higher.ConclusionA validated tool is required to measure KT knowledge. These tools can be used to evaluate the effectiveness of educational interventions in promoting self-management after KT.Protocol registration numberCRD42022334559.
| S-EPMC9888680 | biostudies-literature
Project description:OBJECTIVE: Rigorous human-computer interaction (HCI) design methodologies have not traditionally been applied to the development of clinical trial participant tracking (CTPT) tools. Given the frequent us of iconic HCI models in CTPTs, and prior evidence of usability problems associated with the use of ambiguous icons in complex interfaces, such approaches may be problematic. Presentation Discovery (PD), a knowledge-anchored HCI design method, has been previously demonstrated to improve the design of iconic HCI models. In this study, we compare the usability of a CTPT HCI model designed using PD and an intuitively designed CTPT HCI model. METHODS: An iconic CPTP HCI model was created using PD. The PD-generated and an existing iconic CTPT HCI model were subjected to usability testing, with an emphasis on task accuracy and completion times. Study participants also completed a qualitative survey instrument to evaluate subjective satisfaction with the two models. RESULTS: CTPT end-users reliably and reproducibly agreed on the visual manifestation and semantics of prototype graphics generated using PD. The performance of the PD-generated iconic HCI model was equivalent to an existing HCI model for tasks at multiple levels of complexity, and in some cases superior. This difference was particularly notable when tasks required an understanding of the semantic meanings of multiple icons. CONCLUSION: The use of PD to design an iconic CTPT HCI model generated beneficial results and improved end-user subjective satisfaction, while reducing task completion time. Such results are desirable in information and time intensive domains, such as clinical trials management.
| S-EPMC3225206 | biostudies-other
Project description:Children and young people's participation, as stipulated in the Convention on the Rights of the Child, applies to both matters that directly and indirectly affect children. Participation is in some countries recognized as a fundamental right and children's engagement seen as a valuable resource. Assisted by conceptual understanding of co-creation, children may be enabled to engage and participate in a variety of contexts. Knowledge about research on, and facilitation of, co-creation involving children is the theme of the scoping review presented by this protocol. The protocol outlines a scoping review which is to use a systematic approach to synthesize knowledge of research about co-creation with children. By systematically scoping the existing research about co-creation with children, the review will survey the available literature (evidence), identify key concepts, and uncover gaps in knowledge. The overall objective of this scoping review is to gain knowledge of research conducted about all types of co-creation with children, and to identify the gaps that future research should address. This scoping review acknowledges the existence of multiple definitions of co-creation, which vary depending on different contexts. The review will also recognize several other associated concepts, such as co-production, co-design, co-research, and co- innovation, since they are used interchangeably with or align with the understanding of co-creation being reviewed. The methodological framework outlined by the Joanna Briggs Institute (JBI) for scoping review will be used as a guide for this review. The PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation will be used during the process. The databases, ERIC (Education Resources Information Centre), Teacher Reference Center, Idunn, Oria, Libris, Kungliga biblioteket, ScienceDirect, ProQuest, Scopus, Academic search elite, Web of Science, Google scholar, will be searched for information on academic books and articles, in May 2024. Also grey literature will be searched for relevant academic references. There are no limitations in date of publication. Language will be limited to English, Norwegian, Swedish, and Danish. Following the selection of studies, data will be extracted and analysed. Ethical approval is not required, because only secondary data is collected. Dissemination will include peer-reviewed publications and presentations at conferences regarding public innovation, education, and children`s participations contexts.
| S-EPMC11315329 | biostudies-literature