Genome sequence and comparative genome analysis of Lactobacillus casei: insights into their niche-associated evolution.

ABSTRACT: Lactobacillus casei is remarkably adaptable to diverse habitats and widely used in the food industry. To reveal the genomic features that contribute to its broad ecological adaptability and examine the evolution of the species, the genome sequence of L. casei ATCC 334 is analyzed and compared with other sequenced lactobacilli. This analysis reveals that ATCC 334 contains a high number of coding sequences involved in carbohydrate utilization and transcriptional regulation, reflecting its requirement for dealing with diverse environmental conditions. A comparison of the genome sequences of ATCC 334 to L. casei BL23 reveals 12 and 19 genomic islands, respectively. For a broader assessment of the genetic variability within L. casei, gene content of 21 L. casei strains isolated from various hab

SUBMITTER: Cai H 

PROVIDER: S-EPMC2817414 | biostudies-literature | 2009 Jul

REPOSITORIES: biostudies-literature