Regional regulation of transcription in the chicken genome.

ABSTRACT:

Background

Over the past years, the relationship between gene transcription and chromosomal location has been studied in a number of different vertebrate genomes. Regional differences in gene expression have been found in several different species. The chicken genome, as the closest sequenced genome relative to mammals, is an important resource for investigating regional effects on transcription in birds and studying the regional dynamics of chromosome evolution by comparative analysis.

Results

We used gene expression data to survey eight chicken tissues and create transcriptome maps for all chicken chromosomes. The results reveal the presence of two distinct types of chromosomal regions characterized by clusters of highly or lowly expressed genes. Furthermore, these regions

SUBMITTER: Nie H 

PROVIDER: S-EPMC2817690 | biostudies-literature | 2010 Jan

REPOSITORIES: biostudies-literature